GLP-1 receptor agonists and uses thereof

Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

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Bibliographische Detailangaben
Hauptverfasser:	CURTO, JOHN M, ASPNES, GARY ERIK, LIMBERAKIS, CHRIS, EDMONDS, DAVID JAMES, FLANAGAN, MARK EDWARD, MATHIOWETZ, ALAN MARTIN, RUGGERI, ROGER B, PIOTROWSKI, DAVID WALTER, GRIFFITH, DAVID ANDREW, LONDREGAN, ALLYN TIMOTHY, FUTATSUGI, KENTARO, LIAN, YA-JING, HUARD, KIM, BAGLEY, SCOTT WILLIAM
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.