Improved nucleotide sequences encoding peptide linkers

The invention provides improved nucleotide sequences and nucleic acids that encode glycine serine linkers and that use an excess of GGA, GGG, and GGT/GGU codons to encode the glycine residues. The invention further relates to nucleotide sequences and nucleic acids that encode (fusion) proteins and p...

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Bibliographische Detailangaben
Hauptverfasser: DE FOUGEROLLES, ANTONIN, BRIGE, ANN, STANSSENS, PATRICK, MERCHIERS, TOM, DE BOCK, PIETER-JAN, DE BRABANDERE, VERONIQUE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides improved nucleotide sequences and nucleic acids that encode glycine serine linkers and that use an excess of GGA, GGG, and GGT/GGU codons to encode the glycine residues. The invention further relates to nucleotide sequences and nucleic acids that encode (fusion) proteins and polypeptides comprising glycine serine linkers, which nucleotide sequences and nucleic acids comprise such improved nucleotide sequences and nucleic acids of the invention.