Antibodies and antibody fragments for site-specific conjugation

The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise a substituted cysteine for site-specific conjugation.

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Bibliographische Detailangaben
Hauptverfasser: TCHISTIAKOVA, LIOUDMILA GENNADIEVNA, GRAZIANI, EDMUND IDRIS, MARQUETTE, KIMBERLY ANN, TUMEY, LAWRENCE N, SAPRA, PUJA, MA, DANGSHE, KHANDKE, KIRAN MANOHAR, PRASHAD, NADIRA ANARKALI, BENNETT, ERIC M
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise a substituted cysteine for site-specific conjugation.