Compound and pharmaceutical composition for tumor imaging and tumor therapy

A compound represented by formula (I) is provided, wherein in formula (I), R1 and R2 each independently represents hydrogen, O-R3 or S-R4, at least one of R1 and R2 is O-R3 or S-R4, and R3 and R4 are independently a C1 to C10 alkyl group, such that the C1to C10 alkyl group is non-substituted or subs...

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Hauptverfasser: CHEN, PING-FAN, CHANG, KAII, TSAO, NING, HUANG, HUNG-YUAN, CHANG, WEIUNG, LEE, KUN-HSIN, HUANG, MIN-HUEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A compound represented by formula (I) is provided, wherein in formula (I), R1 and R2 each independently represents hydrogen, O-R3 or S-R4, at least one of R1 and R2 is O-R3 or S-R4, and R3 and R4 are independently a C1 to C10 alkyl group, such that the C1to C10 alkyl group is non-substituted or substituted with at least one selected from the group consisting of -OH, -NH2, halogen, ester, ether, and carboxylic acid, and M being a metal or a metal-containing compound. The compound represented by formula (I) is shown to have higher specificity to tumor cells, and is therefore suitable for carrying anti-cancer drugs and/or nuclear imaging agents. A pharmaceutical composition for tumor imaging and tumor therapy is also provided. formula (I).