SHP2 phosphatase inhibitors and methods of use thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the invention. The present invention further relates to, but is not limited to, methods for treating disorders...

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Bibliographische Detailangaben
Hauptverfasser:	LESCARBEAU, ANDRE, GREISMAN, JACK B, PIERCE, LEVI CHARLES THOMAS, MURCKO, MARK, KELLEY, ELIZABETH H, DAHLGREN, MARKUS KRISTOFER, BHAT, SATHESH, SHORTSLEEVES, KELLEY C, TAYOLOR, ALEXANDER M, MARAGAKIS, PAUL, GIORDANETTO, FABRIZIO, WALTERS, W. PATRICK, DIPIETRO, LUCIAN V, THERRIEN, ERIC
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the invention. The present invention further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds and compositions of the invention.