Composition comprising long-acting erythropoietin

The present invention provides a composition containing long-acting erythropoietin, and a method for preparation thereof. More particularly, there is provided an EPO-Fc fusion protein composition with excellent bio-sustainability and high purity, wherein sialic acid content of EPO-Fc is 17 mol/mol o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HAN, SEUNG-RYEL, KIM, MIN-WOO, CHUNG, YO-KYUNG, WOO, JUNG-WON, SUNG, YOUNGUL, YANG, SE-HWAN, YANG, SANG-IN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides a composition containing long-acting erythropoietin, and a method for preparation thereof. More particularly, there is provided an EPO-Fc fusion protein composition with excellent bio-sustainability and high purity, wherein sialic acid content of EPO-Fc is 17 mol/mol or more, and host-cell derived protein (HCP) impurity is included in an amount of 100 ng/mg or less.