New crystalline form of aripiprazole characterized in that the crystalline form has the property that the differential heat scan at a heating rate of 5 DEG C/min has an endothermic peak at a temperature of approximately 125 DEG C and close to 134 DEG C

The present invention provides a novel crystalline form N of aripiprazole, a pharmaceutical composition thereof, and the use of the crystalline form N in the preparation of a medicament for the treatment of central nervous system disorders (particularly schizophrenia). This invention is characterize...

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Bibliographische Detailangaben
Hauptverfasser:	JIANG, WEI-MING, SUN, YUN-ZHE, LIN, CHENG-GANG, LIU, FEI, GUI, LI, ZHAO, XIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides a novel crystalline form N of aripiprazole, a pharmaceutical composition thereof, and the use of the crystalline form N in the preparation of a medicament for the treatment of central nervous system disorders (particularly schizophrenia). This invention is characterized in that the crystalline form has the property that the differential heat scan at a heating rate of 5 DEG C/min has an endothermic peak at a temperature of approximately 125 DEG C and close to 134 DEG C. Also, the crystalline form has a powder X-ray diffraction spectrum which has the same peak position as that of the powder X-ray diffraction pattern shown in Figure 1.