Use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication capable of increasing the allergic effects of radiation and chemotherapeutic drugs, inhibiting the formation of head and neck tumors and reducing the occurrence of head and neck cancer metastasis

Use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication capable of increasing the allergic effects of radiation and chemotherapeutic drugs, inhibiting the formation of head and neck tumors and reducing the occurrence of head and neck cancer metastasis

The present invention relates to a use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication, a use for suppressing the growth, invasion and metastasis of the head and neck cancer cells, wherein the sequence is 5'-AAAGUGCUUC...

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Hauptverfasser: ZHENG, EN-JIA, LU, YA-QING
Format: Patent
Sprache:chi ; eng
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CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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creator ZHENG, EN-JIA
LU, YA-QING
description The present invention relates to a use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication, a use for suppressing the growth, invasion and metastasis of the head and neck cancer cells, wherein the sequence is 5'-AAAGUGCUUCCUUUUAGAGGG-3 ' (SEQ ID NO: 2). The microRNAs-520b sequence has the function of inhibiting malignant characteristics of head and neck cancer, which can increase the allergic effects of radiation and chemotherapeutic drugs, inhibit the formation of head and neck tumors and reduce the occurrence of head and neck cancer metastasis.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
title Use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication capable of increasing the allergic effects of radiation and chemotherapeutic drugs, inhibiting the formation of head and neck tumors and reducing the occurrence of head and neck cancer metastasis
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