Use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication capable of increasing the allergic effects of radiation and chemotherapeutic drugs, inhibiting the formation of head and neck tumors and reducing the occurrence of head and neck cancer metastasis

The present invention relates to a use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication, a use for suppressing the growth, invasion and metastasis of the head and neck cancer cells, wherein the sequence is 5'-AAAGUGCUUC...

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Bibliographische Detailangaben
Hauptverfasser:	ZHENG, EN-JIA, LU, YA-QING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present invention relates to a use of microRNAs-520b (miR-520b) sequence for suppressing tumor growth and metastasis of head and neck cancer and its medication, a use for suppressing the growth, invasion and metastasis of the head and neck cancer cells, wherein the sequence is 5'-AAAGUGCUUCCUUUUAGAGGG-3 ' (SEQ ID NO: 2). The microRNAs-520b sequence has the function of inhibiting malignant characteristics of head and neck cancer, which can increase the allergic effects of radiation and chemotherapeutic drugs, inhibit the formation of head and neck tumors and reduce the occurrence of head and neck cancer metastasis.