Methods for production of stable chimeric cytokine protein formulations in blow fill seal containers

Provided herein are stable formulations comprising a chimeric cytokine protein (e.g., an IL-1[beta]/IL-1Ra chimeric cytokine protein, e.g., P05) in a blow-fill-seal (BFS) container, and methods of producing chimeric cytokine protein formulations in BFS containers such that the formulations retain st...

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Hauptverfasser: SCHIRMER, EMILY BELCHER, WONG, WAIKEN K, ZARBIS-PAPASTOITSIS, GREGORY, LOWDEN, PATRICIA
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creator SCHIRMER, EMILY BELCHER
WONG, WAIKEN K
ZARBIS-PAPASTOITSIS, GREGORY
LOWDEN, PATRICIA
description Provided herein are stable formulations comprising a chimeric cytokine protein (e.g., an IL-1[beta]/IL-1Ra chimeric cytokine protein, e.g., P05) in a blow-fill-seal (BFS) container, and methods of producing chimeric cytokine protein formulations in BFS containers such that the formulations retain stability.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Methods for production of stable chimeric cytokine protein formulations in blow fill seal containers
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