Methods for production of stable chimeric cytokine protein formulations in blow fill seal containers

Methods for production of stable chimeric cytokine protein formulations in blow fill seal containers

Provided herein are stable formulations comprising a chimeric cytokine protein (e.g., an IL-1[beta]/IL-1Ra chimeric cytokine protein, e.g., P05) in a blow-fill-seal (BFS) container, and methods of producing chimeric cytokine protein formulations in BFS containers such that the formulations retain st...

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Bibliographische Detailangaben
Hauptverfasser: SCHIRMER, EMILY BELCHER, WONG, WAIKEN K, ZARBIS-PAPASTOITSIS, GREGORY, LOWDEN, PATRICIA
Format: Patent
Sprache:chi ; eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided herein are stable formulations comprising a chimeric cytokine protein (e.g., an IL-1[beta]/IL-1Ra chimeric cytokine protein, e.g., P05) in a blow-fill-seal (BFS) container, and methods of producing chimeric cytokine protein formulations in BFS containers such that the formulations retain stability.