Pyrrolo[2,3-B]pyridine CDK9 kinase inhibitors

Disclosed are compounds of formula I: wherein R1, R2, R3, and R4 have any of the values defined therefore in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used to agents in the treatments of diseases, including cancer. Also provided for are pharmaceutical com...

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Hauptverfasser:	TAO, ZHI-FU, JI, ZHI-QIN, ZHU, GUIDONG, MICHAELIDES, MICHAEL, FLORJANCIC, ALAN S, CLARK, RICHARD F, GOSWAMI, RAJEEV, FREY, ROBIN R, SONG, XIAO-HONG, LAI, CHUNQIU, TONG, YUNSONG, GONG, JIANCHUN, RISI, ROBERTO M, MASTRACCHIO, ANTHONY, MIYASHIRO, JULIEM, WOODS, KEITH W, BRUNCKO, MILAN, HANSEN, TODD M, IQUTURI, OMPRAKASH REDDY, DABBEERU, MADHU BABU, CURTIN, MICHAEL L, SOUERS, ANDREW, PENNING, THOMAS
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compounds of formula I: wherein R1, R2, R3, and R4 have any of the values defined therefore in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used to agents in the treatments of diseases, including cancer. Also provided for are pharmaceutical compositions comprising one or more compounds of Formula I.