Vitamin K2 microsphere, manufacture method, use, and drug thereof

The present invention provides a vitamin K2 microsphere (VK2MS), including a poly(lactide-co-glycolide) acid (PLGA) particle, wherein the Mw of PLGA is between 1000 to 300000, and the molar ratio of repeat units PLA to PGA is 1 to 9:9 to 1; and a vitamin K2 embedded in the PLGA particle, wherein vit...

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Hauptverfasser: CHENG, CHUNGIH, YANG, CHIHIANG, WHU, SHU-WEN
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creator CHENG, CHUNGIH
YANG, CHIHIANG
WHU, SHU-WEN
description The present invention provides a vitamin K2 microsphere (VK2MS), including a poly(lactide-co-glycolide) acid (PLGA) particle, wherein the Mw of PLGA is between 1000 to 300000, and the molar ratio of repeat units PLA to PGA is 1 to 9:9 to 1; and a vitamin K2 embedded in the PLGA particle, wherein vitamin K2 is present in an amount of 0.005 to 75 wt %, based on the weight of the microsphere. The invention also provides a manufacture method, use, and a drug thereof.
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language chi ; eng
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subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR RELEVANT APPARATUS
TRANSPORTING
title Vitamin K2 microsphere, manufacture method, use, and drug thereof
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