Vitamin K2 microsphere, manufacture method, use, and drug thereof

The present invention provides a vitamin K2 microsphere (VK2MS), including a poly(lactide-co-glycolide) acid (PLGA) particle, wherein the Mw of PLGA is between 1000 to 300000, and the molar ratio of repeat units PLA to PGA is 1 to 9:9 to 1; and a vitamin K2 embedded in the PLGA particle, wherein vit...

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Bibliographische Detailangaben
Hauptverfasser:	CHENG, CHUNGIH, YANG, CHIHIANG, WHU, SHU-WEN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention provides a vitamin K2 microsphere (VK2MS), including a poly(lactide-co-glycolide) acid (PLGA) particle, wherein the Mw of PLGA is between 1000 to 300000, and the molar ratio of repeat units PLA to PGA is 1 to 9:9 to 1; and a vitamin K2 embedded in the PLGA particle, wherein vitamin K2 is present in an amount of 0.005 to 75 wt %, based on the weight of the microsphere. The invention also provides a manufacture method, use, and a drug thereof.