Method for manufacturing human epidermal cell growth factor

Disclosed is a novel means making possible the manufacture of an epidermal growth factor (EGF) with good efficiency and lower cost than conventional techniques. As a result of thoroughgoing research aimed at developing a technique for producing human EGF using plants, the inventors of the present ap...

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Bibliographische Detailangaben
Hauptverfasser:	OKAWA, SHOUICHIROU, YOSHINAKA, KYOUJI, SATO, SEIYA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is a novel means making possible the manufacture of an epidermal growth factor (EGF) with good efficiency and lower cost than conventional techniques. As a result of thoroughgoing research aimed at developing a technique for producing human EGF using plants, the inventors of the present application succeeded in finding a modified EGF coding sequence and a signal peptide coding sequence that allow production of EGF with high efficiency using a transient expression system. Using these sequences allows EGF to be produced with good efficiency even when the transient expression system of a viral vector is used.