Method for producing self-organizing peptide derivative

An object of the present invention is to provide a method for efficiently producing a self-organizing peptide derivative useful in the regenerative medicine field and the surgical field, and economically obtaining the self-organizing peptide derivative in large quantities. The present invention prov...

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Bibliographische Detailangaben
Hauptverfasser:	YAMAMOTO, KENICHIRO, NAGANO, TOYOHIRO, NAKAMURA, DAISUKE, YOKOI, HIDENORI, MATSUYAMA, KEISUKE, ANZAI, KINSEI, YOKOYAMA, YASUHIRO, KODAMA, KAZUYA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	An object of the present invention is to provide a method for efficiently producing a self-organizing peptide derivative useful in the regenerative medicine field and the surgical field, and economically obtaining the self-organizing peptide derivative in large quantities. The present invention provides a producing method which combines: (i) a convergence sequence building step of using common units of amino acid sequence, and (ii) a step of firstly separating disulfate, tetramethane sulfonate or tetratrifluoroacetic acid (TFA) salts and the like, and then exchanging them to tetrahydrochloride.