Correlation analysis of genetic copy number variants in hyperlipidemia patients with myocardial infarction

This invention relates to an analysis of copy number variants (CNVs) in genomic DNA samples of patients. This invention uses a single nucleotide polymorphism array (SNP array) analysis and the real-time polymerase chain reaction (real-time PCR) to detect the regions with genetic copy number variants...

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Bibliographische Detailangaben
Hauptverfasser: TSAO, YU-MING, KU, TIEN-HSIUNG, HSU, FANG-RONG, SHIA, WEIUNG, TANG, CHUAN-YI
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:This invention relates to an analysis of copy number variants (CNVs) in genomic DNA samples of patients. This invention uses a single nucleotide polymorphism array (SNP array) analysis and the real-time polymerase chain reaction (real-time PCR) to detect the regions with genetic copy number variants, so as to determine whether the copy number variant regions (CNVRs) of the samples are associated with the hyperlipidemia and myocardial infarction, providing as the biomarker for early diagnosis of the hyperlipidemia and myocardial infarction.