Bioavailable compositions of amorphous piperidinyl compounds

This invention relates to solid amorphous dispersions comprising Compound I having the formula or stereoisomers thereof, and one or more polymers. More particularly, this invention relates to bioavailable amorphous solid dispersions of Compound I that are unexpectedly stable in suspension and in the...

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Bibliographische Detailangaben
Hauptverfasser:	SU, CHINGIANG, VIG, BALVINDER S, STEFANSKI, KEVIN J, BETIGERI, SEEMA, HAGEMAN, MICHAEL J, VICKERY, RODNEY D
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to solid amorphous dispersions comprising Compound I having the formula or stereoisomers thereof, and one or more polymers. More particularly, this invention relates to bioavailable amorphous solid dispersions of Compound I that are unexpectedly stable in suspension and in the solid state for extended periods of time that may be used for tabletting.