Quinazolinone-type compounds as CRTH2 antagonists

This application provides for compounds of the formula or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associat...

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Hauptverfasser: KELLEY, ELIZABETH HELEN, HUANG, XIAN-HAI, YU, YOU-NONG, SILIPHAIVANH, PHIENG, ZHOU, WEI, MAZZOLA, ROBERT D. JR, ZHANG, HONG-JUN, MCCORMICK, KEVIN D, QIN, JUN, CALDWELL, JOHN P, BIJU, PURAKKATTLE JOHNY, LEYHANE, ANDREW J, TANG, HAI-QUN, DONG, LI, METHOT, JOEY L, XIAO, DONG, GAUUAN, JOLICIA POLIVINA, PALANI, ANANDAN, MACCOSS, RACHEL N, ASLANIAN, ROBERT G, DHONDI, PAWAN K, BOYCE, CHRISTOPHER W, MCKITTRICK, BRIAN A, SHAO, NING, JIANG, QIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:This application provides for compounds of the formula or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associated with the CRTH2 receptor.