2,3-dihydro-1H-inden-1-yl-2,7-diazaspiro[3.5]nonane derivatives

The present invention provides a compound of Formula (I) (I)or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditio...

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Bibliographische Detailangaben
Hauptverfasser:	LONDREGAN, ALLYN TIMOTHY, CAMERON, KIMBERLY O'KEEFE, MCCLURE, KIM FRANCIS, BHATTACHARYA, SAMIT KUMAR, SIMILA, SUVI TUULA MARJUKKA, KUNG, DANIEL WEI-SHUNG, FERNANDO, DILINIE PRASADHINI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of Formula (I) (I)or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.