New compounds

The present invention relates to novel compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of A -related pathologies such as Downs syndrome, -amyloid angiopathy such as but not limited t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SWAHN, BRITT-MARIE, KOLMODIN, KARIN, VON KIESERITZKY, FREDRIK, VON BERG, STEFAN, GINMAN, TOBIAS, BLID, JAN, GRAVENFORS, YLVA, KARLSTROEM, SOFIA, PLOBECK, NIKLAS, VIKLUND, JENNY, RAHM, FREDRIK, LINDSTROEM, JOHAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of A -related pathologies such as Downs syndrome, -amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (''mild cognitive impairment''), Alzheimer Disease, memory loss, attention deficit symptoms associated with Alzheimer disease, neurodegeneration associated with diseases such as Alzheimer disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.