A novel mothod for preparation of glycidyl phthalimide

Summary: A key intermediate is prepared by potassium phthalimide, ( ± ) -Epichlorohydrin or an optically active epichlorohydrin and quaternany ammonium salt in the presence of solvent and then cyclized with R2CO3 and potassium carbonate in the presence of solvent to obtain Oxazolidinone intermediate...

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Hauptverfasser: SHIH, KAE-SHYANG, LIN, HUI-YIN, LIU, CHING-WEI, HSIEH, YU-JUNG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Summary: A key intermediate is prepared by potassium phthalimide, ( ± ) -Epichlorohydrin or an optically active epichlorohydrin and quaternany ammonium salt in the presence of solvent and then cyclized with R2CO3 and potassium carbonate in the presence of solvent to obtain Oxazolidinone intermediate. The present invention discloses a novel and environmental process for preparing the antibacterial agent Zyvox.