Amino-pyridines as inhibitors of -secretase

The present invention provides an amino-pyridine compound of formula I, The present invention also provides methods for the use thereof to inhibit -secretase (BACE) and treat -amyloid deposits and neurofibrillary tangles.

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Bibliographische Detailangaben
Hauptverfasser:	LOVERING, FRANK ELDRIDGE, FOBARE, WILLIAM FLOYD, ROBICHAUD, ALBERT JEAN, SOLVIBILE, WILLIAM RONALD JR, MALAMAS, MICHAEL SOTIRIOS, CONDON, JEFFREY SCOTT
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides an amino-pyridine compound of formula I, The present invention also provides methods for the use thereof to inhibit -secretase (BACE) and treat -amyloid deposits and neurofibrillary tangles.