Drug delivery system

A drug delivery system consisting of one or more compartments and comprising a progestogenic compound dissolved in a thermoplastic polyethylene vinylacetate copolymer whereby, - if the delivery system consists of one compartment, the compartment comprises (i) a core of a thermoplastic polyethylene v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KRUFT, MARCUS ANTONIUS BERNARDUS, VAN LAARHOVEN, JOHANNES ANTONIUS HENDRIKUS, DE GRAAFF, WOUTER, GROEN, JANNEKE SOPHIE, VROMANS, HERMAN, ZEEMAN, RAYMOND
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	A drug delivery system consisting of one or more compartments and comprising a progestogenic compound dissolved in a thermoplastic polyethylene vinylacetate copolymer whereby, - if the delivery system consists of one compartment, the compartment comprises (i) a core of a thermoplastic polyethylene vinylacetate copolymer comprising the progestogenic compound, such progestogenic compound being dissolved in the polyethylene vinylacetate copolymer up to a concentration below the saturation level at 25 DEG C, and an estrogenic compound; and (ii) a skin of a thermoplastic polyethylene vinylacetate copolymer covering the core, said skin being permeable for both compounds; - if the delivery system consists of more than one compartment, only one compartment comprises (iii) the progestogenic compound, such proges-togenic compound being dissolved in a core of a thermoplastic polyethylene vinylacetate copolymer up to a concentration below the saturation level at 25 DEG C, and an estrogenic compound; and (iv) a skin of a