Novel compounds

Compounds of formula (I): wherein: R1 represents substituted or unsubstituted heterocyclyl; Y represents -(CRnaRnb)n-; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 1 to 5; R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3...

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Hauptverfasser: DUNCAN BRUCE JUDD, GORE, PAUL MARTIN, SIMON TEANBY HODGSON, GAIL MILLS, ELDRED, COLIN DAVID, HARRISON, LEE ANDREW, ANCLIFF, RACHAEL ANN, COOK, CAROLINE MARY, XIAO QING LEWELL, MARK WILKINSON, STEPHEN SWANSON, MARTIN ALISTAIR HAYES, GRAEME MICHAEL ROBERTSON, ANDREW JOHN WALKER, SUZANNE ELAINE KEELING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:Compounds of formula (I): wherein: R1 represents substituted or unsubstituted heterocyclyl; Y represents -(CRnaRnb)n-; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 1 to 5; R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 represents hydrogen or C1-6alkyl; and salts and solvates thereof are CCR-3 antagonists and are thus indicated to be useful in therapy.