COMBINED USE OF ANTITUMOR INDOLOPYRROLOCARBAZOLE DERIVATIVE AND OTHER ANTITUMOR AGENT

This invention relates to a combined preparation for simultaneous; separate; or sequential administration in the treatment of cancer; comprising two separate preparations: a preparation comprising;in combination with a pharmaceutically acceptable carrier or diluent; at least one compound of general formula I: (wherein R1 and R2 each independently represents hydrogen atom; lower alkyl; or the like and G represents a pentosyl or the like; X1 and X2 each independently represents hydrogen atom; a halogen atom;or the like or a pharmaceutically acceptable salt thereof; and; a preparation in combination with a pharmaceutically acceptable carrier or diluent each as anitumor alkylating agents; antitumor antibiotics;plant-derived antitumor agents;(a preparation containing at least one compound of general FORMULA (I) or a pharmaceutically acceptable salt thereof may be combinated with two or more other antitumor agents)and a method for cancer treatement comprising the administration of these operations in combination.