COMPOSES NOUVEAUX ANTAGONISTES DE PPAR, ET COMPOSITIONS LES CONTENANT

L'INVENTION CONCERNE DES COMPOSES DE FORMULE (I): DANS LAQUELLE A, B, E, N, W, Z, R1, R2, R3, R5 ET R6 REPRESENTENT DIVERS RADICAUX. ELLE CONCERNE EGALEMENT DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS COMME ACTIVATEURS DE PPAR - alph...

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Bibliographische Detailangaben
Hauptverfasser:	DAVID AUSTEN PERRY, CHERYL MYERS HAYWARD
Format:	Patent
Sprache:	fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	L'INVENTION CONCERNE DES COMPOSES DE FORMULE (I): DANS LAQUELLE A, B, E, N, W, Z, R1, R2, R3, R5 ET R6 REPRESENTENT DIVERS RADICAUX. ELLE CONCERNE EGALEMENT DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS COMME ACTIVATEURS DE PPAR - alpha POUR LE TRAITEMENT DE DIVERSES MALADIES. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.