FUSION MOLECULES

The present invention relates to fusion molecules that have binding specificity for pyoverdine type 1, Il and Ill and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent o...

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Bibliographische Detailangaben
Hauptverfasser:	JENSEN, Kristian, RASSER, Hans-Falk, STUEDEMANN, Thomas, ALLERSDORFER, Andrea, HÜLSMEYER, Martin, LUNDE, Bradley, KRUIP, Jochen, RAT, Dorothea, REY, Astrid, LANGE, Christian, SCHAEFER, Juergen, FRAISSE, Laurent, HINNER, Marlon, STUMP, Heike, WIEDENMANN, Alexander, CALANDRA, Bernhard, CORVEY, Carsten, FOCKEN, Ingo, MOUREZ, Michael, ROTHE, Christine
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to fusion molecules that have binding specificity for pyoverdine type 1, Il and Ill and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein.