4-METHYL-2,3,5,9,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALENES

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparin...

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Hauptverfasser: HÖFGEN, Norbert, FRATTINI, Sara, GRUNWALD, Christian, STANGE, Hans, GIOVANNINI, Riccardo, DI ANTONIO, Giustino, LANKAU, Hans-Joachim, EGERLAND, Ute, LANGEN, Barbara, BERTANI, Barbara
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.