STABILIZED PHARMACEUTICAL FORMULATIONS OF A POTENT HCV INHIBITOR

Described are various methods for stabilizing pharmaceutical formulations of a specific Hepatitis C Viral (HCV) inhibitor against the formation of a particular genotoxic degradation product. Such methods include temperature control, moisture control, excipient control, capsule shell control, basific...

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Hauptverfasser:	QIU FENGHE, CHEN FENG-JING, BUSACCA CARL ALAN, PENNINO SCOTT, GUMP EDWIN LOUIS, BRAUN MATHIAS, VILLAGRA MARIA FERNANDA, MAJESKA JENNESS B
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Described are various methods for stabilizing pharmaceutical formulations of a specific Hepatitis C Viral (HCV) inhibitor against the formation of a particular genotoxic degradation product. Such methods include temperature control, moisture control, excipient control, capsule shell control, basification and a reconstitution approach.