INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3

INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3

This invention is directed to a 3-(amido or sulphamido )-4-( 4-substituted-azinyl)benzamide or benzsulphonamide compound as defined herein. The 3 -( amido or sulphamido )-(4-substituted-azinyl)benzamide or benzsulphonamide compound is useful as a inhibitor of the chemokine receptor CxCR3, and for pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: THORPE DAVID S, SMRCINA MARTIN, CABEL DAGMAR D
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention is directed to a 3-(amido or sulphamido )-4-( 4-substituted-azinyl)benzamide or benzsulphonamide compound as defined herein. The 3 -( amido or sulphamido )-(4-substituted-azinyl)benzamide or benzsulphonamide compound is useful as a inhibitor of the chemokine receptor CxCR3, and for preventing or treating a CxCR3 chemokine receptor mediated disease or condition related thereto in a patient in need of such.