NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES COMPOSITIONS CONTAINING SAME AND USE THEREOF

The invention relates to the novel substances in Formula (I): wherein Het is a heterocycle optionally substituted by one or a plurality of radicals R1 or R'1; R is selected from the group comprising Formula (II) with R1 and/or R'1 selected from H, halogen, CF3, nitro, cyano, alkyl, hydroxyl, mercapto, amino, alkylamino, dialkylamino, alkoxy, phenylalcoxy, alkythio, or carboxy that is free or esterified by an alkyl, carboxamide, CO-NH(alkyl), CON(alkyl)2, NH-CO-alkyl, sulfonamide, NH-SO2-alkyl, S(O)2-NHalkyl, or S(O2)-N(alkyl)2 radical; all these radicals are optionally substituted; W1, W2, and W3 independently are CH or N; X is O, S, NR2, C(O), S(O), or S(O)2; Z is optionally substituted H, HaI, -O-R2 or -NH-R2 with R2 being H, alkyl, cycloalkyl, or heterocycloalkyl; and these substances are all isomeric forms and salts thereof, used as drugs.