COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to beat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal acti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	REVESZ,LASZLO, CHIANELLI,DONATELLA, BREITEINSTEI, LOREN,JON, MANLEY,PAUL W, LI,XIAOLIN, PEREZ,LAWRENCE B, BROOKS,CLINTON, MOLTENI,VALENTINA, WRONA,WOJCIECH, NABAKKA,JULIET, LIU,XIAODONG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to beat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFR (alpha) and PDGFRl (beta) kinases. Formula (I).