PROCESS FOR PREPARING DERIVATIVES OF ARYL ETHERS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS (MODIFICATIONS)

PROCESS FOR PREPARING DERIVATIVES OF ARYL ETHERS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS (MODIFICATIONS)

The present invention provides aryl ether derivatives of the general formula: +TR wherein A is an oxygen atom or the group >N-R1, R1 being a hydrogen atom or a lower alkyl radical, R2 and R3, which can be the same or different, are hydrogen atoms or lower alkyl radicals, R4 is a hydrogen atom or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OTTO-KHENNING VILKHELMS,DE, VALTER GUNAR FRIBE,DE, VERNER VINTER,DE, MAKS TIL,DE, ANDRONIKI ROESH,DE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention provides aryl ether derivatives of the general formula: +TR wherein A is an oxygen atom or the group >N-R1, R1 being a hydrogen atom or a lower alkyl radical, R2 and R3, which can be the same or different, are hydrogen atoms or lower alkyl radicals, R4 is a hydrogen atom or a hydroxyl group, R5 is a hydrogen atom or an acyl radical, R7 is a hydrogen atom, a lower alkyl radical or a lower alkanoyl radical and R8 is a hydrogen atom, a lower alkyl radical, a lower alkoxy radical or a hydroxyl group; and the pharmacologically acceptable salts thereof. The present invention also provides a process for the preparation of these compounds and pharmaceutical compositions containing them. It is also concerned with the use of these compounds for combating allergic diseases.