PROCESS FOR PRODUCING RACEMIC OR OPTICALLY ACTIVE BROMODERIVATIVES OF 14-OXO-15-HYDROXY-E-HOMOEBURNANES

PROCESS FOR PRODUCING RACEMIC OR OPTICALLY ACTIVE BROMODERIVATIVES OF 14-OXO-15-HYDROXY-E-HOMOEBURNANES

The invention relates to new, racemic or optically active, halogenated 15-hydroxy-E-homoeburnane derivatives of the formulae (Ia) and/or (Ib), (Ia) (Ib) wherein R is a C1-6 alkyl group and X is halogen, and acid addition salts thereof. These compounds are biologically active, furthermore they can be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LAJOSH SABO,HU, CHABA SANTAI,HU, FERENTS DREKSLER,HU, LAJOSH DANCHI,HU, TIBOR KEVE,HU, DERD KALAUSH,HU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to new, racemic or optically active, halogenated 15-hydroxy-E-homoeburnane derivatives of the formulae (Ia) and/or (Ib), (Ia) (Ib) wherein R is a C1-6 alkyl group and X is halogen, and acid addition salts thereof. These compounds are biologically active, furthermore they can be applied as intermediates in the synthesis of other pharmaceutically active substances.