METHOD OF PREPARING 2-DESOXYSTREPTAMINEAMINOGLYCOSIDES OR THEIR SALTS

METHOD OF PREPARING 2-DESOXYSTREPTAMINEAMINOGLYCOSIDES OR THEIR SALTS

Certain 2-deoxystreptamine aminoglycoside antibiotics, substituted on the 1-amino group by an alkyl group bearing one or more hydroxy groups, are useful antibacterial agents. The 2-deoxystreptamine aminoglycoside compounds which are substituted in this manner include the kanamycins, the gentamicins,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ROUNA MARGARET PLYUS,GB, DZHEJMS ROBERT RAJT,GB, KENNET RICHARDSON,GB
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:Certain 2-deoxystreptamine aminoglycoside antibiotics, substituted on the 1-amino group by an alkyl group bearing one or more hydroxy groups, are useful antibacterial agents. The 2-deoxystreptamine aminoglycoside compounds which are substituted in this manner include the kanamycins, the gentamicins, tobramycin, ribostamycin, the neomycins, and 6'-N-alkyl derivatives thereof.