METHOD OF PRODUCING TRIPHENYLALKENE DERIVATIVES

Novel triphenyl-alkene derivatives and process for preparing same The invention relates to novel triphenylalkene derivatives of the general formula I (I) wherein R denotes a C1-4 alkyl group and X stands for a halogen atom, with the restriction that when R denotes a methyl group, then X may denote o...

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Hauptverfasser: EDEN FEKHER,HU, ENDRE CHANI,HU, TIBOR KHORVAT,HU, ILONA SENTE,HU, LAJOSH TOLD,HU, GIZELLA ABRAKHAM,HU, GEZA SHNAJDER,HU
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creator EDEN FEKHER,HU
ENDRE CHANI,HU
TIBOR KHORVAT,HU
ILONA SENTE,HU
LAJOSH TOLD,HU
GIZELLA ABRAKHAM,HU
GEZA SHNAJDER,HU
description Novel triphenyl-alkene derivatives and process for preparing same The invention relates to novel triphenylalkene derivatives of the general formula I (I) wherein R denotes a C1-4 alkyl group and X stands for a halogen atom, with the restriction that when R denotes a methyl group, then X may denote only a halogen atom other than chlorine, and their geometrical isomers. Furthermore, the invention relates to a process for the production of these compounds. The compounds according to the invention can be used for the preparation of Tamoxifen, a known agent against ???illary ??ncer, and of related compounds. Furthermore, they possess a valuable biological activity.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD OF PRODUCING TRIPHENYLALKENE DERIVATIVES
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