METHOD OF PRODUCING TRIPHENYLALKENE DERIVATIVES

METHOD OF PRODUCING TRIPHENYLALKENE DERIVATIVES

Novel triphenyl-alkene derivatives and process for preparing same The invention relates to novel triphenylalkene derivatives of the general formula I (I) wherein R denotes a C1-4 alkyl group and X stands for a halogen atom, with the restriction that when R denotes a methyl group, then X may denote o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: EDEN FEKHER,HU, ENDRE CHANI,HU, TIBOR KHORVAT,HU, ILONA SENTE,HU, LAJOSH TOLD,HU, GIZELLA ABRAKHAM,HU, GEZA SHNAJDER,HU
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Novel triphenyl-alkene derivatives and process for preparing same The invention relates to novel triphenylalkene derivatives of the general formula I (I) wherein R denotes a C1-4 alkyl group and X stands for a halogen atom, with the restriction that when R denotes a methyl group, then X may denote only a halogen atom other than chlorine, and their geometrical isomers. Furthermore, the invention relates to a process for the production of these compounds. The compounds according to the invention can be used for the preparation of Tamoxifen, a known agent against ???illary ??ncer, and of related compounds. Furthermore, they possess a valuable biological activity.