METHOD OF PREPARING ANTHRACYCLINES
Daunorubicin (also known as daunomycin) derivatives of the formula I wherein X is and R is -COCF3 or H which are prepared by hydrogenating 9-desacetyl-9-keto-N-trifluoroacetyldaunorubicin, an unexpectedly stable key-intermediate which is itself a new compound, are useful in treating certain mammalia...
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creator | FEDERIKO ARKAMONE,IT SERDZHO PENKO,IT FRANCHESKO ANDZHELUCHCHI,IT |
description | Daunorubicin (also known as daunomycin) derivatives of the formula I wherein X is and R is -COCF3 or H which are prepared by hydrogenating 9-desacetyl-9-keto-N-trifluoroacetyldaunorubicin, an unexpectedly stable key-intermediate which is itself a new compound, are useful in treating certain mammalian tumors. |
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subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
title | METHOD OF PREPARING ANTHRACYCLINES |
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