METHOD OF OBTAINING 15-SUBSTITUTED PROSTANE DERIVATIVES OR SALTS THEREOF

1446341 Silylated prostaglandins PFIZER Inc 13 July 1973 [13 July 1972] 31217/73 Heading C3S [Also in Division C2] 11α,15α - Bis - (dimethylisopropylsilyloxy)- 9 - oxo - 16 - (2 - thienyl) - 17,18,19,20 - tetranor - trans - 13 - prostenoic acid is prepared by hydrogenating 11α,15α - bis - (dimethyli...

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Hauptverfasser: MAJKL ROSS DZHONSON (SSHA),US, GANS-YURGEN ERNST GESS (FRG),DT, DZHASIT SINGKH BINDRA (INDIYA),IN, TOMAS KEN SHAAF (SSHA),US
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Sprache:eng
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Zusammenfassung:1446341 Silylated prostaglandins PFIZER Inc 13 July 1973 [13 July 1972] 31217/73 Heading C3S [Also in Division C2] 11α,15α - Bis - (dimethylisopropylsilyloxy)- 9 - oxo - 16 - (2 - thienyl) - 17,18,19,20 - tetranor - trans - 13 - prostenoic acid is prepared by hydrogenating 11α,15α - bis - (dimethylisopropylsilyloxy) - 9 - oxo - 16 - (2 - thienyl)- 17,18,19,20 - tetranor - cis - 5, trans - 13- prostadienoic acid, obtained by reacting dimethylisopropyl chlorosilane with 11α,15α- dihydroxy - 9 - oxo - 16 - (2 - thienyl) - 17,18, 19,20 - tetranor - cis - 5 trans - 13 - prostadienoic acid.