METHOD OF OBTAINING N-(2-BENZHYDRYLETHYL)-N-(1-PHENYLETHYL)-AMINE RACEMATE, ITS OPTICALLY ACTIVE ANTIPODES OR THEIR SALTS

METHOD OF OBTAINING N-(2-BENZHYDRYLETHYL)-N-(1-PHENYLETHYL)-AMINE RACEMATE, ITS OPTICALLY ACTIVE ANTIPODES OR THEIR SALTS

A process for the preparation of the compound of the formula I and its salts is described. It is based on the reduction of the acid amide of the formula II. The reduction is advantageously carried out using a complex metal hydride. The compound of the formula I forms racemates, the synthesis claimed...

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Bibliographische Detailangaben
Hauptverfasser: DEZHE KORBONITSH,HU, PAL KISHSH,HU, KALMAN KHARSHANI,HU, ENRE PALOSHI,HU
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A process for the preparation of the compound of the formula I and its salts is described. It is based on the reduction of the acid amide of the formula II. The reduction is advantageously carried out using a complex metal hydride. The compound of the formula I forms racemates, the synthesis claimed leading to the optically active components. Under the name phendilin, the final substance is used pharmaceutically against angina pectoris.