N-TOLUYL HYDRAZINE OF MALEIC ACID POSSESSING ANTIHYPOXIA ACTIVITY

FIELD: medicine. SUBSTANCE: desired product has essential formula CHNO, its melting point being 181-182 C (with decomposition). Hydrazide of p-toluyl acid is used as reagent 1, maleic anhydride being used as reagent 2. Reaction is carried out in the medium of acetonitrile. Yield of desired product i...

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Hauptverfasser:	Koz'minykh V.O, Bormotova S.V, Zykova N.A, Syropjatov B.Ja
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine. SUBSTANCE: desired product has essential formula CHNO, its melting point being 181-182 C (with decomposition). Hydrazide of p-toluyl acid is used as reagent 1, maleic anhydride being used as reagent 2. Reaction is carried out in the medium of acetonitrile. Yield of desired product is 98 %. EFFECT: improves quality of desired product. 1 tbl Использование: в медицине, как соединение, обладающее противогипоксической активностью. Сущность изобретения: продукт п-толуилгидразид малеиновой кислоты, БФ C H NOвыход 98%, т.пл. 181-182С (разл.). Реагент 1: гидразид п-толуиловой кислоты. Реагент 2: малеиновый ангидрид. Условия реакции: в среде ацетонитрила. 1 табл.