METHOD OF OBTAINING 9-OXIME DERIVATIVES OF PERYTHROMYCIN A

A method for the selective methylation of a hydroxy group at the 6-position of an erythromycin A derivative comprises converting an erythromycin A derivative into an erythromycin A 9-oxime derivative, and reacting the resulting erythromycin A 9-oxime derivative with a methylating agent.

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Bibliographische Detailangaben
Hauptverfasser:	SIGEO MORIMOTO, GASAKI ADATI, TOSIFUMI ASAKA, TADASI EGUTI, MASAMI GOI, KAORU SOTA, DZOZI NAKAGAMI, MORIKHIRO MITSUKUTI, KSIAKI VATANABE
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	A method for the selective methylation of a hydroxy group at the 6-position of an erythromycin A derivative comprises converting an erythromycin A derivative into an erythromycin A 9-oxime derivative, and reacting the resulting erythromycin A 9-oxime derivative with a methylating agent.