METHOD OF OBTAINING 2-BROM-ALPHA-ERGOCRYPTINE OR ACID-ADDITIVE SALTS THEREOF

The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.

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Bibliographische Detailangaben
Hauptverfasser: MARIYA GAZDAG,HU, ERIK BOGSH,HU, FERENTS TRISHLER,HU, GABOR SEPESHI,HU, GABOR MEDERI,HU, LAJOSH KOVACH,HU, ANNA KASHSHAI,HU, TIBOR KEVE,HU, BELA SHTEFKO,HU
Format: Patent
Sprache:eng ; rus
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Beschreibung
Zusammenfassung:The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.