METHOD OF PRODUCING PYRROLOBENZIMIDAZOLES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS OF INORGANIC ACIDS
Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alk...
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creator | KLAUS SHTRAJN,DE JENS-PETER KHELK,DE VOLFGANG KAMPE,DE BERND MYULLER-BEKMANN,DE ALFRED MERTENS,DE GISBERT SHPONER,DE |
description | Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1-C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof. |
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The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1-C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1989</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890515&DB=EPODOC&CC=SU&NR=1480770A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890515&DB=EPODOC&CC=SU&NR=1480770A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KLAUS SHTRAJN,DE</creatorcontrib><creatorcontrib>JENS-PETER KHELK,DE</creatorcontrib><creatorcontrib>VOLFGANG KAMPE,DE</creatorcontrib><creatorcontrib>BERND MYULLER-BEKMANN,DE</creatorcontrib><creatorcontrib>ALFRED MERTENS,DE</creatorcontrib><creatorcontrib>GISBERT SHPONER,DE</creatorcontrib><title>METHOD OF PRODUCING PYRROLOBENZIMIDAZOLES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS OF INORGANIC ACIDS</title><description>Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1-C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1989</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQAHvxIOof9gOFSoV63SZps5BmQ5Ie2kspkp5EC_X_qOADPM1hhtlnS6eiZgncgPMse0G2BTd4z4ZrZUfqSOLIRgVgD1Er8uD0EOjjWxJozACCO4eRaqMgoInhOyPLvkVLAlCQDMdst8z3LZ1-PGTQqCh0ntbnlLZ1vqVHek2hP1-uRVUVWJZ_JG-uHjVg</recordid><startdate>19890515</startdate><enddate>19890515</enddate><creator>KLAUS SHTRAJN,DE</creator><creator>JENS-PETER KHELK,DE</creator><creator>VOLFGANG KAMPE,DE</creator><creator>BERND MYULLER-BEKMANN,DE</creator><creator>ALFRED MERTENS,DE</creator><creator>GISBERT SHPONER,DE</creator><scope>EVB</scope></search><sort><creationdate>19890515</creationdate><title>METHOD OF PRODUCING PYRROLOBENZIMIDAZOLES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS OF INORGANIC ACIDS</title><author>KLAUS SHTRAJN,DE ; JENS-PETER KHELK,DE ; VOLFGANG KAMPE,DE ; BERND MYULLER-BEKMANN,DE ; ALFRED MERTENS,DE ; GISBERT SHPONER,DE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SU1480770A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>1989</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KLAUS SHTRAJN,DE</creatorcontrib><creatorcontrib>JENS-PETER KHELK,DE</creatorcontrib><creatorcontrib>VOLFGANG KAMPE,DE</creatorcontrib><creatorcontrib>BERND MYULLER-BEKMANN,DE</creatorcontrib><creatorcontrib>ALFRED MERTENS,DE</creatorcontrib><creatorcontrib>GISBERT SHPONER,DE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KLAUS SHTRAJN,DE</au><au>JENS-PETER KHELK,DE</au><au>VOLFGANG KAMPE,DE</au><au>BERND MYULLER-BEKMANN,DE</au><au>ALFRED MERTENS,DE</au><au>GISBERT SHPONER,DE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF PRODUCING PYRROLOBENZIMIDAZOLES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS OF INORGANIC ACIDS</title><date>1989-05-15</date><risdate>1989</risdate><abstract>Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1-C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | METHOD OF PRODUCING PYRROLOBENZIMIDAZOLES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS OF INORGANIC ACIDS |
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