METHOD OF PRODUCING PYRROLOBENZIMIDAZOLES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS OF INORGANIC ACIDS

Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alk...

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Hauptverfasser:	KLAUS SHTRAJN,DE, JENS-PETER KHELK,DE, VOLFGANG KAMPE,DE, BERND MYULLER-BEKMANN,DE, ALFRED MERTENS,DE, GISBERT SHPONER,DE
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula (I) wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1-C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.