DERIVATIVES OF THIAZOLIDINE-4S-CARBOLIC ACID OFFERING HEPATIC PROTECTION
The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl o...
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Format: | Patent |
Sprache: | eng ; rus |
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Zusammenfassung: | The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin. |
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