METHOD OF PRODUCING (1-IMIDAZOLYL-CARBONYL)-7/3-3-(3-PYRIDIL)-H,3H-PYRROLE-(1,2-C)-THIAZOLE

New compounds of the formula (I) in which R1 and R2=H or alkyl and (a) R=CN or alkylcarbonyl, or (b) R=CON(R3)R4, in which R3=H and R4=NH2, alkylamino, dialkylamino, phenylamino or diphenylamino; or R3 and R4=H, alkyl (1 to 5 C) or substituted phenyl; or R3=H and R4=pyridyl or alkyl (1 to 5 C) substituted by COOH, NH2, alkylamino, dialkylamino, morpholino, piperidino, pyrrolidin-1-yl, piperazin-1-yl (optionally substituted by alkyl, pyridyl or optionally substituted phenyl or benzyl), optionally substituted phenyl, pyridyl or imidazolyl; or R3 and R4 form an imidazolyl radical or a 5-membered or 6-membered heterocycle which can contain an oxygen, sulphur or nitrogen atom and which is optionally substituted by alkyl, alkoxycarbonyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, pyridyl, pyrimidinyl, pyrazinyl, optionally substituted phenyl or optionally substituted benzyl; or (c) R=-C(=NOH)NH2 or -C[=NN(R'R'')NH2], in which R' and R''=alkyl, the said alkyl radicals and alkyl portions being straight-chain or branched-chain and, unless mentioned otherwise, containing 1 to 4 carbon atoms, and the substituted phenyl and benzyl radicals carrying a halogen atom or an alkyl, alkoxy, alkylthio, trifluoromethyl or dialkylamino radical, and their tautomeric forms, addition salts with acids and the metals salts and the addition salts with nitrogen bases, are useful anti-allergic and anti-inflammatory agents. A variety of methods of making them are described.