METHOD OF OBTAINING DERIVATIVES OF DIBENZIMIDASOAZEPINE OR SALTS THEREOF

Compounds of the formula wherein R1, R2, R3 and R4 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; R5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkenyl of 3 to 6 carbon atoms; R6 is alkyl of 1 to 6 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl, ha...

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Hauptverfasser: GERKHARD VALTER,DE, KARL-GEJN VEBER,DE, ARMIN FYUGNER,DE, KLAUS SHNEJDER,DE
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of the formula wherein R1, R2, R3 and R4 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; R5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkenyl of 3 to 6 carbon atoms; R6 is alkyl of 1 to 6 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl, halo-phenyl, lower alkyl-phenyl, or lower alkoxy-phenyl or R7 and R8 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy or 1 to 6 carbon atoms; n is an integer from 0 to 4, inclusive; x is -O-, -S-, or -CH2-; and the broken line between the 10 and 13b-positions indicates a single or double bond; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as antiallergics and antithrombotics.