PROCESS FOR PREPARING DERIVATIVES OF NORTHROPANOLE OR THEIR SALTS

PROCESS FOR PREPARING DERIVATIVES OF NORTHROPANOLE OR THEIR SALTS

Compounds of the formula wherein Ar is R1 is hydrogen, fluorine, bromine, methyl or methoxy; X is =CO, =CH-CN, =CH-OH, -O-, -S-, -NH-, +TR and R is hydrogen, 4-fluoro, 4-chloro, 4-trifluoromethyl, 3-trifluoromethyl, 3-trifluoromethyl-4-chloro, 4-methyl or 4-methoxy; and non-toxic, pharmacologically...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ADOLF LANGBEJN,DE, GERBERT MERTS,DE, RUDOLF BAUER,DE, KHANS MIKHAEL IENNEVEJN,DE, RAJNER SOBOTTA,DE, JOAKHIM MIRAU,DE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of the formula wherein Ar is R1 is hydrogen, fluorine, bromine, methyl or methoxy; X is =CO, =CH-CN, =CH-OH, -O-, -S-, -NH-, +TR and R is hydrogen, 4-fluoro, 4-chloro, 4-trifluoromethyl, 3-trifluoromethyl, 3-trifluoromethyl-4-chloro, 4-methyl or 4-methoxy; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as neuroleptics.